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These are the most downloaded papers for the 30 days preceding April 13, 2011.

1. Quaternary Structure of SecA in Solution and Bound to SecYEG Probed at the Single Molecule Level
Ilja Kusters, Geert van den Bogaart, Alexej Kedrov, Victor Krasnikov, Faizah Fulyani, Bert Poolman, Arnold J.M. Driessen
Summary | |
9 March 2011
19(3)
2. ePMV Embeds Molecular Modeling into Professional Animation Software Environments
Graham T. Johnson, Ludovic Autin, David S. Goodsell, Michel F. Sanner, Arthur J. Olson
Summary | |
9 March 2011
19(3)
3. Mechanism-Based Strategies for Trapping and Crystallizing Complexes of RNA-Modifying Enzymes
Amandine Guelorget, Béatrice Golinelli-Pimpaneau
Summary | |
9 March 2011
19(3)
4. The Contribution of Entropy, Enthalpy, and Hydrophobic Desolvation to Cooperativity in Repeat-Protein Folding
Tural Aksel, Ananya Majumdar, Doug Barrick
Summary | |
9 March 2011
19(3)
5. Heat Maps for Intramolecular Communication in an RNP Enzyme Encoding Glutamine
Annia Rodríguez-Hernández, John J. Perona
Summary | |
9 March 2011
19(3)
6. Alternate Modes of Cognate RNA Recognition by Human PUMILIO Proteins
Gang Lu, Traci M. Tanaka Hall
Summary | |
9 March 2011
19(3)
7. The Mechanisms of HAMP-Mediated Signaling in Transmembrane Receptors
Hedda U. Ferris, Stanislaw Dunin-Horkawicz, Laura García Mondéjar, Michael Hulko, Klaus Hantke, Jörg Martin, Joachim E. Schultz, Kornelius Zeth, Andrei N. Lupas, Murray Coles
Summary | |
9 March 2011
19(3)
8. X-ray Crystal Structure of the UCS Domain-Containing UNC-45 Myosin Chaperone from Drosophila melanogaster
Chi F. Lee, Arthur V. Hauenstein, Jonathan K. Fleming, William C. Gasper, Valerie Engelke, Banumathi Sankaran, Sanford I. Bernstein, Tom Huxford
Summary | |
9 March 2011
19(3)
9. Structural Characterization of the Boca/Mesd Maturation Factors for LDL-Receptor-Type β Propeller Domains
Mark N. Collins, Wayne A. Hendrickson
Summary | |
9 March 2011
19(3)
10. Combining Bayes Classification and Point Group Symmetry under Boolean Framework for Enhanced Protein Quaternary Structure Inference
Pralay Mitra, Debnath Pal
Summary | |
9 March 2011
19(3)
11. Two Structural and Functional Domains of MESD Required for Proper Folding and Trafficking of LRP5/6
Jianglei Chen, Chia-Chen Liu, Qianqian Li, Christian Nowak, Guojun Bu, Jianjun Wang
Summary | |
9 March 2011
19(3)
12. Intrinsic Bending of Microtubule Protofilaments
Andrea Grafmüller, Gregory A. Voth
Summary | |
9 March 2011
19(3)
13. The physiological structure of human C-reactive protein and its complex with phosphocholine
Darren Thompson, Mark B Pepys, Steve P Wood
Summary | |
15 February 1999
7(2)
14. Interferon-Inducible Protein 16: Insight into the Interaction with Tumor Suppressor p53
Jack C.C. Liao, Robert Lam, Vaclav Brazda, Shili Duan, Mani Ravichandran, Justin Ma, Ting Xiao, Wolfram Tempel, Xiaobing Zuo, Yun-Xing Wang et al.
Summary | |
9 March 2011
19(3)
15. Beyond the Random Coil: Stochastic Conformational Switching in Intrinsically Disordered Proteins
Ucheor B. Choi, James J. McCann, Keith R. Weninger, Mark E. Bowen
Summary | |
13 April 2011
19(4)
16. Crystal Structure of a Human Cleavage Factor CFIm25/CFIm68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping
Qin Yang, Molly Coseno, Gregory M. Gilmartin, Sylvie Doublié
Summary | |
9 March 2011
19(3)
17. Structural and Energetic Determinants of Apo Calmodulin Binding to the IQ Motif of the NaV1.2 Voltage-Dependent Sodium Channel
Michael D. Feldkamp, Liping Yu, Madeline A. Shea
Summary | |
24 March 2011
18. The Structure of MESD45–184 Brings Light into the Mechanism of LDLR Family Folding
Christian Köhler, Janet K. Lighthouse, Tobias Werther, Olav M. Andersen, Annette Diehl, Peter Schmieder, Jianguang Du, Bernadette C. Holdener, Hartmut Oschkinat
Summary | |
9 March 2011
19(3)
19. Peering Down the Barrel of a Bacteriophage Portal: The Genome Packaging and Release Valve in P22
Jinghua Tang, Gabriel C. Lander, Adam Olia, Rui Li, Sherwood Casjens, Peter Prevelige, Gino Cingolani, Timothy S. Baker, John E. Johnson
Summary | |
13 April 2011
19(4)
20. Pumilio RNA Recognition: The Consequence of Promiscuity
Sean P. Ryder
Summary | |
9 March 2011
19(3)